Houston Office: 713-900-3900

New York Office: 212-686-7306

Search Icon
call us

Clinical Trials

Melasma study: laser combined with the tranexamic acid pill

Seeking healthy non-smoking male and female volunteers of all skin types of age 18 to 65 with moderate melasma or severe melasma. Participants will receive up to 5 monthly laser treatments to half the face and need to take a pill twice a day for 4 months. Follow up visits are required 1 month, 3 months and 6 months after the final treatment.  Compensation of up to $150 will be provided based on completed visits.

Inclusion Criteria:

  • Healthy male and female subjects between the ages 18 to 65
  • Fitzpatrick skin types I through VI (all skin types)
  • Moderate or severe melasma
  • Willing to participate in study photography
  • Able and willing to comply with all visit, treatment, and evaluation schedules
  • Able to understand and provide written informed consent

Exclusion Criteria:

  • Pregnant, nursing women, current use of hormonal birth control medication or any hormonal therapy, or history of >2 spontaneous abortions
  • Use of topical steroids on the face within 1 month of study enrollment, use of topical hydroquinone on the face within 3 months of study enrollment, laser or dermabrasion to the face within 6 months of study enrollment
  • Regular use of tanning parlors, or occupation involving primarily outdoor activities
  • Current treatment with blood thinning medications
  • History of thrombosis, thrombophilia, or thromboembolic disease, such as deep vein thrombosis, pulmonary embolism and/or cerebral thrombosis, family history of thromboembolic disease
  • History of seizures or known light sensitive seizure disorder, stroke, or subarachnoid hemorrhage
  • History of kidney dysfunction
  • History of cancer, or active smoking
  • Significant cardiovascular or respiratory disease (end-stage congestive heart failure or chronic obstructive pulmonary disease)
  • History of acquired disturbances of color vision
  • Known allergy to tranexamic acid
  • As per the investigator’s discretion, any physical or mental condition which might make it unsafe for the subject to participate in this study

For More Information Contact The Research Department At
(212) 686-7306 or research@laserskinsurgery.com